Transplant Immunology I: Immunological Mechanisms of Graft Injury

Surgery 24: 47, 2006 –

Solid-organ transplantation has enjoyed great success over the last twenty years. Graft survival after kidney, liver or heart transplantation exceeds 90% at one year and is about 50% at 10 years in most centres in the UK. Better immunosuppressive drugs and more thorough understanding of the nature of the immune response against the graft are the reasons for this success.

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