PUBLICATIONS/PUBLICATIONS ARCHIVE

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(November 27, 2015)
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(November 26, 2015)
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(November 26, 2015)
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(November 26, 2015)
Categories: Publications
(November 26, 2015)
Categories: Publications
(November 26, 2015)
Categories: Publications
(November 26, 2015)
Categories: Publications
(November 26, 2015)
Categories: Publications
(November 26, 2015)
Categories: Publications
(November 26, 2015)
Categories: Publications
(November 26, 2015)
Categories: Publications
(December 31, 2008)
Summary: In renal allograft recipients transplanted for IgA nephropathy (IgAN) the disease recurs in 40-60% of cases. However, disease progression is moderated by immunosuppression. In this study we evaluated renal transplantation outcomes in recipients with IgAN.
Categories: Publications
(December 15, 2008)
Summary: Journal of Viral Hepatitis, 2005, 12, 627–634 – Hepatitis C virus (HCV) transmission by both seropositive and seronegative cadaver organ donors has been documented, yet nucleic acid testing is not routinely used to identify active infection in these donors prior to transplantation. Between November 2001 and February 2004, we screened 1445 cadaver organ donors for […]
Categories: Publications
(August 31, 2008)
Summary: The Journal of Urology (in press), 2009 – Testing immunotherapeutic strategies for prostate cancer has been impeded by the lack of relevant tumor models in immunocompetent animals. This opportunity is now provided by the recent development of prostate specific PTEN knockout mice, which show spontaneous development of true adenocarcinoma arising from prostate epithelium and more […]
Categories: Publications
(August 15, 2008)
Summary: This study aims to determine the association of CYP3A5(A6986G) and ABCB1 exon 12 (C1236T), exon26(C3435T) with early renal function in 318 kidney transplant patients.
Categories: Publications
(August 14, 2008)
Summary: Recent advances in vector technology now allow the possibility of genetically engineering graft tissues to express reduced levels of HLA. Reducing HLA expression could help to overcome the limitations imposed by polymorphisms which restrict availability of suitable donors, complicate logistics of procuring and delivering matched tissues and organs, and necessitate life-long immunosuppression. We have previously […]
Categories: Publications
(August 14, 2008)
Summary: Gastrointestinal (GI) symptoms are the most common complications with mycophenolic acid (MPA) therapy. MRP2 and UGT2B7 which are involved in the excretion and production of the metabolites of MPA respectively may play a role in the presentation of GI symptoms.
Categories: Publications
(August 13, 2008)
Summary: The development of diabetes after transplantation is a significant problem that dramatically increases patient morbidity and mortality. The principle cause of NOPTDM is the use of diabetogenic drugs, especially steroids and calcineurin inhibitors (CNIs), and yet only a proportion of recipients develop the disease. This suggests an individuality in susceptibility that may have a genetic […]
Categories: Publications
(August 12, 2008)
Summary: Recent studies demonstrated better outcomes of graft and patient survival in living donor liver transplantation (LDLT) compared with those of whole liver (WLT) and split liver transplantation (SLT). However their results often utilize recipients from both pre and post model-for-end-stage- liver disease (MELD/PELD) implementation.
Categories: Publications
(August 11, 2008)
Summary: Polyomavirus-associated nephropathy often precedes renal allograft dysfunction in adult renal transplant recipients. The OPTN/UNOS began collecting information regarding polyomavirus test results using followup forms since June 30, 2004. The aim of this study is to evaluate the impact of clinical polyomavirus disease (PVD) on graft survival after pediatric kidney transplantation
Categories: Publications
(August 11, 2008)
Summary: IL-6 is a key pro-inflammatory cytokine unregulated after Brain Death (BD) in humans. It leads to adhesion molecule activation and leukocyte invasion in all organs. Pre-explantation organ dysfunction is a direct consequence of inflammation, and renders many organs unsuitable for transplantation. Functionally, IL-6 elevation correlates with deteriorating donor cardiac function in humans and its unregulation […]
Categories: Publications
(August 11, 2008)
Summary: As a possible consequence of public disclosure of center survival rates in the United States, organs from consenting donors may not be utilized because of a low expected benefit to the recipient. This study examines the reasons for non-utilization with the aim of identifying characteristics of organs not suitable for transplantation in the United States, […]
Categories: Publications
(July 31, 2008)
Summary: Trypanosoma cruzi, a parasite that causes Chagas disease, is endemic in parts of Mexico, South and Central America. Transmission of T. cruzi infection by solid organ transplantation has been reported in Latin America and United States1 (Figure 1). Our laboratory began to test organ donors for anti-T. cruzi using FDA’s approved EIA on April 15, […]
Categories: Publications
(July 31, 2008)
Summary: Transmission of hepatitis B virus infection through hepatitis B core antibody positive (HBcAb+) grafts to hepatitis B surface antigen negative (HBsAg- recipients has been reported (Liver Int. 2005 Dec;25(6):1169-74). The mandatory use of immunosupression in transplant patients favors reactivation of latent virus that may be present in grafts from HBsAg-negative anti-HBc-positive donors. With the persistent […]
Categories: Publications
(July 31, 2008)
Summary: Clin Pharmacol Ther. 83: 711-717, 2008 – Inosine 50-monophosphate dehydrogenase 1 (IMPDH1) catalyzes the rate-limiting step of the de novo pathway for purine synthesis and is a major target of the immunosuppressive drug mycophenolic acid (MPA). Few variants of theIMPDH1 gene have been reported. The objective of this study was to identify and characterize IMPDH1 […]
Categories: Publications
(July 31, 2008)
Summary: Clin Exp Nephrol. 12: 41-52, 2008 – Clinical practice guidelines for management of chronic kidney disease (CKD) have been developed within the Kidney Disease Outcomes Quality Initiative (K/DOQI). Adherence patterns may identify focus areas for quality improvement.
Categories: Publications
(July 31, 2008)
Summary: Previous reports and NIT Laboratory data support the existence of persistent HCV RNA viremia in the absence of detectable anti-HCV1. Experience from blood donor screening suggests that the nucleic acid testing (NAT) can reduce so-called “window period” donations from organ donors during the antibody negative phase of acute HCV or HIV-1 infections2. In Sep 04’ […]
Categories: Publications
(July 31, 2008)
Summary: AIDS Res Hum Retroviruses. 24: 163-168, 2008 – Evidence indicates that immunosupression is associated with the development of certain cancers. The pathogenesis of HIV disease includes an alteration in innate immunity, mediated through NK and NKT cells. The evaluation of innate immune status in HIV patients prior to cancer diagnosis may identify the specific immunological […]
Categories: Publications
(July 31, 2008)
Summary: Immunol Res. (in press) 2008 – Current approaches for hematopoietic stem cell (HSC) and organ transplantation are limited by donor and host-mediated immune responses to allo-antigens. Application of these therapies is limited by the toxicity of preparative and post-transplant immunosuppressive regimens and a shortage of appropriate HLA-matched donors. We have been exploring two complementary approaches […]
Categories: Publications
(May 31, 2008)
Summary: Despite improved early graft survival (currently over 90% at 1-year) long-term graft loss rate has not been reduced. Both HLA antibodies and HLA donor specific antibodies (DSA) have been shown to contribute to acute and chronic allograft nephropathy (CAN), particularly the former. In a longitudinal study, HLA antibodies were linked to graft failure. Recently, Class […]
Categories: Publications
(May 31, 2008)
Summary: It is very important to investigate whether specific pediatric allocation schemes can not only lead to minimization of waiting time, but also to better clinical outcomes for children with end-stage renal disease (ESRD).
Categories: Publications
(May 31, 2008)
Summary: Polyomavirus-associated nephropathy often precedes renal allograft dysfunction in adult renal transplant recipients. The Organ Procurement and Transplant Network/ the United Network for Organ Sharing (OPTN/UNOS) began collecting information regarding polyomavirus test results using follow-up forms since June 30, 2004. The aim of this study was to evaluate the impact of clinical polyomavirus disease (PVD) on […]
Categories: Publications
(May 31, 2008)
Summary: Polymorphisms in several genes on the short arm of chromosome 6 (6p), among them VEGF (6p12), FKBP5 (6p21.2), HLA-DR (6p21.3) and TNF-a (6p21.3), have been associated with inflammation and transplant outcome. Each of these genes is associated with acute rejection. Independent segregation of these genes is unproven, so we investigated linkage between distant genes on […]
Categories: Publications
(May 31, 2008)
Summary: There is currently a lack of predictive methods to define glucocorticoid (GC) sensitivity, which is extremely variable among individuals. In particular, identifying patients in whom steroids will have immunosuppressive and toxic activities is important in transplantation. Therefore we have sought to establish an in vitro pharmacokinetic assay to investigate leukocyte proliferation and cytokine production, with […]
Categories: Publications
(May 31, 2008)
Summary: Initial high dose steroid treatment of transplant recipients induces changes in the cytoplasmic glucocorticoid receptor (cGR) that may affect the mode of action of the drug. The cGR consists of functionally distinct isoforms of the GR and chaperone molecules, including FK binding protein 5 (FKBP5), that modulate GR signaling. Normal sensitivity to steroids requires expression […]
Categories: Publications
(May 31, 2008)
Summary: Despite improved early graft survival long-term graft loss rate hasn’t been reduced. Both HLA antibodies and HLA donor specific antibodies (DSA) have been shown and causal in acute and chronic allograft nephropathy (CAN) particularly the former. In a longitudinal study, HLA antibodies were linked to graft failure. Recently, Class II DSA has been shown correlated […]
Categories: Publications
(May 31, 2008)
Summary: Despite improved early graft survival, long-term kidney graft loss rate has not been reduced. Both HLA antibodies and HLA donor specific antibodies (DSA) have been detected and may be causal in chronic allograft nephropathy (CAN) and, especially, in acute rejection. We evaluated the association between DSA, C4d staining in transplant and graft outcome.
Categories: Publications
(May 31, 2008)
Summary: HLA matching is important and necessary for renal and bone marrow transplants (Curr Opin Organ Transpl 2004 9:1-7, NEJM 1990.323:1818-1822). Zero-mismatched renal transplants are associated with fewer rejection episodes and longer graft survival, and require less immunosuppression. In adult bone marrow transplantation, it is necessary to have no more than one allele mismatch to obtain […]
Categories: Publications
(May 31, 2008)
Summary: It is very important to investigate whether specific pediatric allocation schemes can not only lead to minimization of waiting time, but also to better clinical outcomes for children with end-stage renal disease (ESRD).
Categories: Publications
(May 31, 2008)
Summary: Alport Syndrome accounts for approximately 1% of kidney transplants. It is a hereditary cause of kidney failure associated with hearing loss, more often affecting males than females. Loss of kidney function is attributed to collagen defects in the glomerular basement membrane. Formation of antibody reactive to normal collagen in the transplanted kidney may increase the […]
Categories: Publications
(May 31, 2008)
Summary: Incidences of type 2 diabetes mellitus (DM) are significantly different among different ethnic groups in a general population. A new onset post transplant diabetes mellitus (PTDM) is an important complication after kidney transplantation and is associated with reduced overall patient and graft survival.
Categories: Publications
(May 31, 2008)
Summary: Elderly recipients older than age 50 have increased 3-year rates of posttransplant diabetes (17% vs 4% compared to those younger than 30). This study examines the relative impact of steroids, calcineurin inhibitors, anti-proliferatives and induction therapies on the risk of post-transplant diabetes, rejection and graft loss.
Categories: Publications
(May 31, 2008)
Summary: Alport Syndrome is an X-linked progressive glomerular basement disorder with a prevalence of 1/50,000 live births. This retrospective analysis of data reported to the Organ Procurement Transplant Network examines outcomes associated with the disease.
Categories: Publications
(May 31, 2008)
Summary: Since 2000, despite the shortage of kidneys from deceased donors for transplantation, only about 100 kidney transplants each year were performed with donors older than age 70. Kidneys from these older donors represent only 6% of those allocated in the United States as expanded criteria donors. In this study, we examine how these kidneys might […]
Categories: Publications
(May 31, 2008)
Summary: The 20-60 simultaneous heart-kidney (SHK) transplants performed in the United States every year provide a unique setting for comparing transplant care provided by nephrologists and cardiologists. This study examines rates of heart and kidney rejection and graft loss in the thoracic and kidney analytic files provided by the Organ Procurement Transplant Network.
Categories: Publications
(May 31, 2008)
Summary: Transplantation. 85: 62-68, 2008 – The organ shortage has resulted in increased use of kidneys from expanded criteria donors (ECD). For ECD kidneys unsuitable for single use, dual kidney transplants (DKT) may be possible. There are limited data comparing outcomes of DKT to single kidney ECD transplants, making it unclear where DKT fits in the […]
Categories: Publications
(May 31, 2008)
Summary: Transplantation. 85(11): 1573-1579, 2008 – The organ shortage has resulted in more use of older deceased donor kidneys. Data are limited on the impact of donor aged 70 years and older on transplant outcomes. We examined patient and graft outcomes of renal transplant from expanded criteria donors (ECDs) aged 70 years and older, using the […]
Categories: Publications
(February 29, 2008)
Summary: Am J Kidney Dis. 51: 478-486, 2008 – Gastrointestinal complications after kidney transplantation are associated with inferior graft outcomes. We examined the incidence, risk factors, and outcomes of posttransplantation diarrhea.
Categories: Publications
(December 31, 2007)
Summary: Renal transplantation is considered the best treatment option for patients with ESRD caused by SLE. Many studies have shown a positive outcome for these patients. In our study we looked retrospectively at the outcome of transplanted SLE patients in UNOS data.
Categories: Publications
(December 31, 2007)
Summary: Polyomavirus associated nephropathy is an increasingly recognized cause of allograft dysfunction and failure in kidney transplant recipients. Since June 30, 2004, the Organ Procurement and Transplantation Network/the United Network for Organ Sharing (OPTN/UNOS) has been collecting data on clinical polyomavirus (BK) disease (CPVD) using follow-up record. The aim of this study is to evaluate the […]
Categories: Publications
(December 31, 2007)
Summary: There is a critical shortage of organs available for transplantation. To combat the growing discrepancy between patients on the wait list and available donor kidneys, the United Network for Organ Sharing introduced a policy in 2001 for the use of expanded criteria deceased organ donors. These expanded criteria donors are defined as deceased donors older […]
Categories: Publications
(December 31, 2007)
Summary: Diabetes mellitus (DM) is an important cause of end-stage renal disease worldwide, around 25% of renal transplant recipients have DM as their primary disease for renal failure. Diabetic patients have more complications pre and post renal transplant with increased morbidity: wound healing, infection, and cardiovascular complications which affects their graft and patient survival.
Categories: Publications
(June 30, 2007)
Summary: Am J Transplant 7: 1770-1777, 2007 – The incidence of acute graft rejection and short-term graft survival in renal transplantation have shown considerable improvement in the past decade (1,2). However the gains obtained from the reduction of acute rejection and improvement in graft survival in the first year following transplantation has not resulted in a […]
Categories: Publications
(June 30, 2007)
Summary: Am J Transplant. 7: 2704-2711, 2007 – Recent literature reviews combining the results from over 300 articles estimated the prevalence of poor immunosuppression compliance among kidney transplant recipients to be between 22 and 28% (1,2). Twenty percent of late acute rejections and 16% of graft losses were attributed in part to poor compliance (2). Other […]
Categories: Publications
(June 30, 2007)
Summary: Acta Obstet Gynecol Scand. 86: 903-908, 2007 – To investigate the hypothesis that women who are genetically programmed to produce higher levels of transforming growth factor-beta 1 are more likely to develop severe eclampsia/pre-eclampsia.
Categories: Publications
(June 30, 2007)
Summary: Hum Immunol. 68: 342-349, 2007 – Studies of human immunodeficiency virus (HIV) infection often compare values from HIV-uninfected controls, including CD4 and CD8 lymphocyte counts. Nonetheless, little is known regarding factors associated with CD4 and CD8 cell numbers in HIV uninfected individuals. To ascertain potential factors associated with differences in CD4 and CD8 cells among […]
Categories: Publications
(June 30, 2007)
Summary: Transplantation. 84: 821-828, 2007 – The use of alemtuzumab for induction therapy in kidney transplantation has been increasing. Herein is a report of graft outcomes associated with alemtuzumab induction from the Organ Procurement and Transplantation Network/United Network for Organ Sharing database.
Categories: Publications
(June 30, 2007)
Summary: Cancer Res. 67: 5345-5353, 2007 – Replication-competent retrovirus (RCR) vectors are intrinsically incapable of infecting quiescent cells and have been shown to achieve highly efficient and tumor-restricted replicative spread and gene transfer in vivo after direct intratumoral injection in a variety of primary cancer models. However, i.v. delivery of RCR vectors expressing therapeutic genes has […]
Categories: Publications
(June 30, 2007)
Summary: Transplant Proc. 38: 3184-3188 – Transplantation of many tissues requires histocompatibility matching of human leukocyte antigens (HLA) to prevent graft rejection, to reduce the level of immunosuppression needed to maintain graft survival, and to minimize the risk of graft-versus-host disease, particularly in the case of bone marrow transplantation. However, recent advances in fields of gene […]
Categories: Publications
(June 30, 2007)
Summary: Oral Dis. 13: 208-313, 2007 – To investigate the role of the polymorphism of a variable numbers of tandem repeats of interleukin-1 receptor antagonist gene (IL-1RN) on gingivitis in children.
Categories: Publications
(June 30, 2007)
Summary: Clin J Am Soc Nephrol. 2: 517-523, 2007 – Risk for new-onset diabetes (NOD) after renal transplantation is higher with tacrolimus (Tac) than with cyclosporine (CsA), but the extent to which the diabetogenic effect of Tac is dosage dependent or steroid dependent remains uncertain. Patients who received a transplant between 1995 and 2002 were drawn […]
Categories: Publications
(June 30, 2007)
Summary: Transplantation. 84: 1399-1405, 2007 – Although the degree of glomerulosclerosis on pretransplant donor biopsy is one criterion used in the decision to accept a deceased donor kidney, its relationship with graft survival remains controversial. This study compared graft survival with the degree of glomerulosclerosis found on donor biopsy. We also examined the agreement in degree […]
Categories: Publications
(December 31, 2006)
Summary: Hepatocyte Growth factor (HGF) is a plieotropic hormone which possesses important cardioprotective properties. It attenuates the death of cardiomyocytes and coronary endothelial cells under ischaemic stress, and promotes angiogenesis. Early following myocardial injury, levels of HGF rise in proportion to the size of injured area. Cardiac allografts are subjected to considerable ischaemia and reperfusion stress. […]
Categories: Publications
(December 31, 2006)
Summary: Genomics 17: 283-290, 2006 – Inosine 50-monophosphate dehydrogenase 2 is required for purine synthesis in activated lymphocytes. Variants in the IMPDH2 gene may account for the large inter-individual variability in baseline enzyme activity, immunosuppressive efficacy and side effects in transplant recipients receiving mycophenolic acid. Therefore, the objective of this study was to identify and functionally […]
Categories: Publications
(December 31, 2006)
Summary: Gut 55: 863-868, 2006 – The cytotoxic T lymphocyte antigen 4 (CTLA-4) gene encodes for a membrane bound (mCTLA-4) and a soluble (sCTLA-4) isoform, which are both involved in regulation of T cell function. The CTLA-4 +49A/G single nucleotide polymorphism (SNP) influences expression of mCTLA-4; +6230G/A SNP affects the production of sCTLA-4.
Categories: Publications
(December 31, 2006)
Summary: Transplantation. 82: 1298-1303, 2006 – There may be an allograft-enhancing effect by the liver on the renal allograft in the setting of simultaneous combined liver-kidney transplantation (CLKT) from the same donor. This study was performed to investigate whether an existing liver allograft could protect a kidney allograft from immunologic injury due to histoincompatibility in liver […]
Categories: Publications
(December 31, 2006)
Summary: Transplantation. 82: 1673-1676, 2006 – New-onset diabetes mellitus after kidney transplantation (NODM) is an important co morbid condition that is associated with inferior graft and patient survival. The objective of this study was to identify donor, recipient and transplant factors, and choices of immunosuppression associated with development of NODM using Organ Procurement Transplant Network/United Network […]
Categories: Publications
(December 31, 2006)
Summary: Surgery 24: 79, 2006 – The major strategies in overcoming acute and chronic rejection are to minimize immune activation to reduce the number of T-cells in the recipient to prevent activation and proliferation of T-cells, and to suppress inflammation. Etc.
Categories: Publications
(December 31, 2006)
Summary: Surgery 24: 47, 2006 – Solid-organ transplantation has enjoyed great success over the last twenty years. Graft survival after kidney, liver or heart transplantation exceeds 90% at one year and is about 50% at 10 years in most centres in the UK. Better immunosuppressive drugs and more thorough understanding of the nature of the immune […]
Categories: Publications
(December 31, 2006)
Summary: Transplantation 82: 1210-1213, 2006 – Human T-cell lymphotrophic virus (HTLV) type I has been linked to adult T-cell leukemia/lymphoma (ATL) and HTLV-I associated myelopathy (HAM). Transmission of HTLV by blood and organ transplantation has been documented, with some infections leading to clinical disease. Organ donors are tested for anti-HTLV antibodies and donor suitability is determined […]
Categories: Publications
(December 31, 2006)
Summary: Transplantation. 81: 477-479, 2006 – Trypanosoma cruzi, a parasite that causes Chagas’ disease, is endemic in parts of Mexico, South America, and Central America. Transmission of T. cruzi infection by solid organ transplantation has been reported in Latin America and recently in the United States. To determine the prevalence of T. cruzi antibodies in Southern […]
Categories: Publications
(December 31, 2006)
Summary: Am J Transplant. 6: 1473-1478, 2006 – The use of expanded criteria donors (ECD) has been proposed to help combat the discrepancy between organ availability and need. ECD kidneys are associated with delayed graft function (DGF) and worse long-term survival. The aim of this study is to evaluate the impact of pulsatile perfusion (PP) on […]
Categories: Publications
(December 31, 2006)
Summary: Transplantation 82: 716-717, 2006 – The utilization of donation-aftercardiac-death (DCD) donors in liver transplantation has been proposed as a way to alleviate the shortage of liver allografts. Although the use of DCD livers is increasing, there has been reluctance because of extended warm ischemic times and possible suboptimal allografts. Therefore these DCD livers tend to […]
Categories: Publications
(December 31, 2006)
Summary: Clin J Am Soc Nephrol. 1: 288-296, 2006 – The risk for and predictors of atrial fibrillation (AF) after kidney transplantation are not well described. Registry data that were collected by the United States Renal Data System were used to investigate retrospectively new-onset AF among adult first renal allograft recipients and transplant candidates who received […]
Categories: Publications
(December 31, 2006)
Summary: Pediatr Allergy Immunol 17: 578-582, 2006 – T lymphocytes accumulating in the skin of patients with atopic dermatitis (AD) have a prolonged survival and are key mediators of this inflammatory disease. The anti-apoptotic bfl-1 gene is unique in that it is the only member of the Bcl-2 family that is transcriptionally regulated by inflammatory cytokines […]
Categories: Publications
(December 31, 2006)
Summary: Am J Transplant. 6: 1682-1688, 2006 – The chronic shortage of deceased kidney donors has led to increased utilization of donation after cardiac death (DCD) kidneys, the majority of which are procured in a controlled setting. The objective of this study is to evaluate transplantation outcomes from uncontrolled DCD (uDCD) donors and evaluate their utility […]
Categories: Publications
(December 31, 2006)
Summary: Pharmacogenomics J. 6: 301-310, 2006 – The promise of drug individualization through pharmacogenomics will be evident initially in those patients who have the poorest therapeutic response or most severe adverse drug effects. In solid-organ transplantation, lung transplantation has the poorest outcome among the commonly transplanted major organs with less than 80% one-year and less than […]
Categories: Publications
(December 31, 2006)
Summary: Ann Thoac Surg. 81:132-137, 2006 – A systemic inflammatory response is not uncommonly observed after coronary revascularization. Tumor necrosis factor alpha is one of a number of modulators of this response. A functional polymorphism within the TNFa gene at position G-308A has been associated with increased TNFa levels. The relationship between predicted TNFa genotype and […]
Categories: Publications
(December 30, 2006)
Summary: Transplantation. 81:392-397, 2006 – Recurrent hepatitis C virus (HCV) infection is particularly aggressive in the post liver transplantation setting, with rapid progression of liver fibrosis. Platelet-derived growth factor (PDGF) is reportedly involved in the pathogenesis of liver fibrosis. The aim of this study was to evaluate the possible contribution of molecular variants of the PDGF-B […]
Categories: Publications
(December 30, 2006)
Summary: Transplantation. 82:1677-1682, 2006 – Variations in the expression and activity levels of the multidrug-resistance MDR1/ABCB1 encoded glycoprotein (P-gp) have an impact on the therapeutic efficacy of many drugs. C3435T and G2677 polymorphisms of the MDR1/ABCB1 gene correlate with cellular expression levels of P-gp, a membrane-bound efflux pump which removes a multitude of drugs, including chemotherapy […]
Categories: Publications
(July 31, 2006)
Summary: American Journal of Transplantation 2006: 6
Categories: Publications