FUNDED GRANTS

Following are examples of grants that have been funded by the Mendez National Institute of Transplantation Foundation:

Principal Investigators: Jennifer Unger, Nicole Mendez, Yasir Qazi
Project Title: Kidney Transplant Video Novela Project
Amount of Award: $80,000
Note: UniHealth Foundation awarded a grant of $599,887 and MNITF awarded an additional $80,000 to complete the Project
Published in:
Efficacy of a telenovela designed to improve health literacy and behavioral intentions among Hispanic patients with end-stage renal disease in Southern California (Currently under Peer Review at USC)
Presented at:
National Kidney Foundation Spring Conference, Las Vegas 2014
ESRD Network of Texas Conference – Nephrology Today & Tomorrow 2014 (October 2014)



Principal Investigators
:  Marek J Nowicki, Claudia Chinchilla-Reyes
Project Title: Development and Implementation of Nucleic Acid Screening for HIV, HCV and HBV among organ and Tissue Donors in the United States.
Amount of Award: $150,000
Published in:
1. Am J Transplant. 2011 Jun;11(6):1201-8. Estimated risk of human immunodeficiency virus and hepatitis C virus infection among potential organ donors from 17 organ procurement organizations in the United States.
2. AIDS. 2011 Mar 13;25(5):619-23. Absence of reproducibly detectable low-level HIV viremia in highly exposed seronegative men and women.
Presented at:
Several international meetings including 2013 American Transplant Congress, 2014 World Transplant Congress and at 2014 ICAAC.



Principal Investigators
:  Marek J Nowicki, Claudia Chinchilla-Reyes
Project Title: Increased Threat Of Vector-Borne West Nile Virus Infections Among Organ And Tissue Donors In Western United States
Amount of Award: $100,000
Published in:
1. Transplantation. 2014 May 15;97(9):881-9. Donor-derived West Nile virus infection in solid organ transplant recipients: report of four additional cases and review of clinical, diagnostic, and therapeutic features.
2. Emerg Infect Dis. 2013;19(9):1518-20. West Nile virus RNA in tissues from donor associated with transmission to organ transplant recipients.
Presented at:
American Transplant Congress, 2013
American Transplant Congress, 2010
World Transplant Congress, Berlin 2009



Principal Investigators
:  Marek J Nowicki, Claudia Chinchilla-Reyes
Project Title: HTLV-I/II screening for Organ and Tissue Donors
Amount of Award: $50,000
Transplantation. 2006 Nov 15;82(9):1210-3. High seroprevalence of anti-HTLV-I/II antibodies among solid organ donors necessitates confirmatory testing.
Published in:
1. Transplantation. 2006 Nov 15;82(9):1210-3. High seroprevalence of anti-HTLV-I/II antibodies among solid organ donors necessitates confirmatory testing.
2. Am J Transplant. 2010 Feb;10(2):207-13. Donor screening for human T-cell lymphotrophic virus 1/2: changing paradigms for changing testing capacity.
Presented at:
American Transplant Congress, 2012



Principle Investigator:
 James Cicciarelli, PhD
Co-Investigators: Nathan Lemp, PhD & Noriyuki Kasahara, MD, PhD
Organization: Viracor-IBT Laboratories, Inc.
Project Title: Improving the Identification of HLA Antibodies: The IgG Subclass Assay
Amount of Award: $25,120



Principle Investigator:
Marek Nowicki, PhD
Co-Principle Investigator: Michael Koss, MD
Co-Investigator: Youngil Chang, MD
Organization: Viracor-IBT Laboratories, Inc.
Project Title: Donors with isolated (“HBcAB only”) antibodies to HBV nucleocapsid seropositivity: true evidence for past exposure or laboratory artifacts?
Amount of Award: $21,529



Principle Investigator:
 Nikole Neidlinger, MD
Co-Investigator: Peter Chin-Hong, MD
Organization: California Transplant Donor Network
Project Title: Prevalence in Coccidiodomycosis in Population of Organ Donation at a Single Organ Procurement Organization
Amount of Award: $50,000



Principle Investigator:
Nicole Theodorpolous, MD
Co-Investigator: Michael G. Ison, MD, MS
Organization: The Ohio State University
Project Title: Screening Deceased Organ Donors for HIV, Hepatitis B and Hepatitis C Viruses with Nucleic Acid Testing
Amount of Award: $50,000



Principle Investigator:
Harry Prince, PhD
Co-Investigator:
Michelle Altrich, PhD
Organization:
Viracor-IBT, Laboratories, Inc.
Project Title:
Epidemiology of a new anthropod-transmitted virus: first assessment of Chikungunya virus (ChikV) prevalence among deceased organ and tissue donors
Amount of Award:
$23,000


Principle Investigator: Mara McAdams DeMarco, PhD
Co-Investigator: Jeremy Watson, MD
Organization: Johns Hopkins University
Project Title: Prehabilitation for Adults with End-Stage Renal Disease on the Kidney Transplant Waitlist
Amount of Award: $50,000


Principle Investigator: Xi Ren, PhD.
Co-Investigator: Harold Ott, MD
Organization: Massachusetts General Hospital – Harvard University
Project Title: Inducing pulomonary microvascular specification from hiPSCs by resembling their native niche
Amount of Award: $50,000


Principle Investigator: Kentaro Kitano, MD, PhD
Co-Investigator: Harold Ott, MD
Organization: Massachusetts General Hospital – Harvard University
Project Title: Building transplantable intestine from patient derived cells
Amount of Award: $50,000


Principle Investigator: David Min, PharmD, FCCP, FASHP
Co-Investigator: Youngil Chang, PharmD
Organization: Western University of Health Sciences
Project Title: Glycosylation pattern as a novel diagnostic marker for antibody mediated rejection in kidney transplant patients
Amount of Award: $49,575


Principle Investigator: Maralyn Smith, PhD
Co-Investigator: Scott M. Cowden, MS; Gerald Morris, MD, PhD; Michelle L. Altrich, PhD; & Jeff D. Hester, PhD
Organization: Viracor-IBT Laboratories, Inc.
Project Title: Universal Noninvasive Detection of Solid Organ Transplant Rejection
Amount of Award: $50,000


Principle Investigator: Katrin Hacke, PhD
Co-Investigator: Noriyuki Kasahara, MD, PhD; James Cicciarelli, PhD; & Nathan Lemp,PhD
Organization: University of Miami
Project Title: Genome Editing of Stem Cells for In Vivo Chemoselection & Immunomodulation
Amount of Award: $74,999


Principle Investigator: Manikkan Suthanthiran, MD, FACP
Co-Investigator: Darshana Dadhania, MD; Thangamani Muthukumar, MD; & John R. Lee, MD
Organization: Joan & Sanford I Weill Medical College of Cornell University
Project Title: Massively Parallel RNA Sequencing & Metabolamics: A Multiplatform Approach for the Discovery & Validation of Noninvasive Biomarkers of Kidney Allograft Status
Amount of Award: $50,000


Principle Investigator: James Cicciarelli, PhD
Co-Investigator: Nathan Lemp, PhD; & Noriyuki Kasahara, MD, PhD
Organization: Viracor-IBT Laboratories, Inc.
Project Title: HLA Class Monitoring II Matching Effect on Kidney Transplantation
Amount of Award: $22,500



Principle Investigator:
Philip F. Halloran, MD, PhD
Co-Principle Investigator: Kieran M. Halloran, MD
Co-Investigator: Konrad S. Famulski, PhD, DSc
Organization: University of Alberta, Edmonton, Alberta, Canada
Project Title: Development of a molecular phenotyping system for biopsies from lung transplants
Amount of Award: $100,000



Principle Investigator:
Lindsey R. Bayden, MD
Co-Principle Investigator: Ann E. Woolley, MD, MPH
Organization: Brigham & Woman’s Hospital
Project Title: Transplanting Thoracic Organs from Hepatitis C Positive Donors to Hepatitis C Uninfected Recipients: Proof of Concept Trial
Amount of Award: $149,084 (24 months)