High Seroprevalence of Anti-HTLV-I/II Antibodies Among Solid Organ Donors Necessitates Confirmatory Testing

Transplantation 82: 1210-1213, 2006 –

Human T-cell lymphotrophic virus (HTLV) type I has been linked to adult T-cell leukemia/lymphoma (ATL) and HTLV-I associated myelopathy (HAM). Transmission of HTLV by blood and organ transplantation has been documented, with some infections leading to clinical disease. Organ donors are tested for anti-HTLV antibodies and donor suitability is determined primarily by results from enzyme immunoassays (EIA). Confirmatory testing is not routinely performed, and the number of false positive organ donors is unknown.

Paper-012.pdf download View | Download
Categories: Publications