Hepatocyte Growth factor (HGF) is a plieotropic hormone which possesses important cardioprotective properties. It attenuates the death of cardiomyocytes and coronary endothelial cells under ischaemic stress, and promotes angiogenesis. Early following myocardial injury, levels of HGF rise in proportion to the size of injured area. Cardiac allografts are subjected to considerable ischaemia and reperfusion stress. This study analyses early postoperative levels of HGF and associates them with ischaemic time and outcome.