A Retrospective Analysis of Immunosuppression Compliance, Dose Reduction and Discontinuation in Kidney Transplant Recipients

Am J Transplant. 7: 2704-2711, 2007 –

Recent literature reviews combining the results from over 300 articles estimated the prevalence of poor immunosuppression compliance among kidney transplant recipients to be between 22 and 28% (1,2). Twenty percent of late acute rejections and 16% of graft losses were attributed in part to poor compliance (2). Other literature reviews have suggested that the impact of compliance on graft loss may be even greater in children (3–5).

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